Hispanic, Black, American Indian, and Alaska Native people are twice as likely to die from COVID-19 infection and one and a half times more likely to be infected than White Americans, exemplifying racism within the United States health care system. Learn about racism as a social determinant of health, best practices for antiracist work, and how health care professionals have spearheaded racial and health equity initiatives through awareness, medical education, patient care, and shifting organizational cultures of health systems.